• The Personalized Serum bottle with its cap off beside it and two golden drops in front.
  • A hand pressing the serum pump over the back of the other hand, a golden drop on the skin.
  • A hand holding the Personalized Serum bottle.
  • A woman holding the Personalized Serum bottle beside her face.

All-in-One Personalized Serum

4.9 (116 reviews)

A clarifying formula that gently exfoliates skin and effectively unclogs pores for a clear, even-toned complexion. Infused with almond-derived mandelic acid, known for its exfoliating, firming, and brightening properties, and plumping sodium hyaluronate, this hydrating blend deeply soothes and protects the skin barrier. Rounded out with antioxidant-rich green tea extract and niacinamide, this serum softens wrinkles and dark spots while unclogging pores and blemishes. The result: Visibly clear, radiant, balanced skin.

Free shipping
Dr. Stanley HollmigDr. Amy YuanDr. Nicholas Conley
Reviewed by PROVEN's science board
Dr. Stanley Hollmig, MD, plus our physics and chemistry leads.

Proof

Real skin. Real change.

Real people, real concerns — documented across their PROVEN subscriptions.

Before and after results for Kimberly C. — Acne · Redness
"It's so clear and I can go without makeup and it looks amazing. I used to be so ashamed to walk around with no makeup, had terrible acne! This has been a game changer for me!"
Kimberly C.Acne · Redness

Persistent inflammatory acne + barrier disruption = gentle sebum balance + barrier rebuild system.

1 of 6
Acne · 1 of 6

Clinical results

  • 78%

    Measurable improvement
    on every concern

    12-week third-party clinical trial

  • +34%

    Stronger skin barrier
    by week 4

    Instrument-measured trial

  • 91%

    Of subscribers reorder
    past month three

    PROVEN subscription data

The Diagnostic

47 factors. Read together.

Because your skin isn't shaped by just one thing — and a formula built around one input misses the rest.

Concerns

Hyperpigmentation, fine lines, sensitivity, breakouts — every concern you flag becomes a factor in your formula. Each one gets weighted by severity, not treated in isolation.

Environment

UV index, humidity, hard water, air quality, altitude — read by your ZIP code and refined every shipment. Where you live shapes what your skin needs as much as what you do.

Lifestyle

Sleep, stress, hydration, screen time, sun exposure, alcohol, exercise — the daily inputs that quietly change how your skin behaves. Updated whenever you tell us what's changed.

Biology

Age, gender, skin type, skin tone, pregnancy — the foundation your formula is built on. Determines which actives are safe and at what concentrations.
Macro close-up of skin showing texture, fine lines and hyperpigmentation
Your Concerns6 mapped
  • Redness — severity 82 of 100
  • Loss of firmness — severity 74 of 100
  • Hyperpigmentation — severity 68 of 100
  • Sensitivity — severity 56 of 100
  • Fine lines — severity 42 of 100
  • Acne — severity 31 of 100

Your Formula

Clinical-grade actives. Calibrated.

Each formula draws from a library of 100+ ingredients — chosen, dosed, and sequenced for your skin.

Dark spots lifted, tone evened.

Pigment runs on four mechanisms: synthesis, transfer, inflammation, and slow turnover. Your Serum addresses synthesis, with Arbutin dosed to your tone and the depth of your spots.

  • Arbutin

    Arbutin

    Inhibits melanin for brighter skin

    HyperpigmentationUneven skin toneUV DamageInsufficient Sleep

Your Ritual

How to use.

Morning and night — your whole routine takes under three minutes.

  1. Step 1Start with clean skin

    Cleanse, and tone if that's part of your routine. The serum goes on before anything heavier.

  2. Step 2One to two pumps

    Apply and give it a moment to absorb. The water-based texture sinks in fast.

  3. Step 3Then your moisturizer

    Follow with your Day Moisturizer in the morning, or your Night Cream before bed.

  4. Step 4Morning and night

    Use it every day. Your skin recalibrates over 8–12 weeks, and your formula evolves right along with it.

Product credentials

  • Developed with
    Dermatologists
  • Made
    in USA
  • Cruelty
    Free
  • U.S.
    Patented
  • Clean
    Ingredients
  • Non-Toxic
    Ingredients

From the community

Real skin. Real routines.

Unfiltered video from real members — find the story that looks like yours.

Reviews

4.9/ 5

116 reviews

  • 5 stars91%
  • 4 stars9%
  • 3 stars0%
  • 2 stars0%
  • 1 star0%
Filter reviews by concern

  • It's good!

    Love the fact it's not animal tested !! Hoping to get the serum and duo eye but would like to test it out first as the price is pretty high. So far I have been using the cleanser and moisturizer and pretty happy with it so far.

    Arti

  • It’s magical

    My skin loves the balanced moisturizer

    Debra M.

  • Fantastic!

    I love the serum. It reduces pores, leaves a smooth glow without being sticky.

    Tammy R.

  • Serum

    Love that it has spf

    Marie K.

  • Great Addition

    This is a perfect addition to my basic skin care routine.

    Verona P.

  • Helped clear acne and even skin tobe

    Yay!

    Tatia W.

Showing 6 reviews

Read all 116 reviews

All questions

Can I use it more than once a day?

Yes. The Serum can be used twice a day.

When in my skincare routine should I apply it?

After cleansing (and toning if applicable), before your moisturizer. Apply 1-2 pumps, wait for absorption, then apply your moisturizer.

Can I layer my serum with other products?

Yes. Apply your Serum first, then follow with your Day Moisturizer or Night Cream.

Does the serum contain strong actives?

Ingredients vary based on your personalization. Some formulas may include brightening or smoothing ingredients, while others may focus on hydration or comfort. Your quiz results guide the selection and strength of each active.

How is my Serum personalized?

Your Serum is powered by PROVEN’s Skin Health Index™—our revolutionary skincare database built from billions of validated data points, including peer-reviewed research, clinical studies, and real-world insights. Our SkintellectAI™ technology then translates those insights into precise, personalized formulations that adapt to your unique skin profile, environment, and evolving needs.

How long until I see results?

First visible differences — tone, hydration, comfort — show up around week 2 for most customers. Deeper changes (texture, firmness, pigment, fine lines) build over 8–12 weeks as the actives accumulate. The 12-week mark is when most customers see measurable change across every concern their formula was built to address.

Will my formula actually change over time?

Yes. Adaptive Formula reviews your profile before every shipment — against the season, your skin's reported progress, and any change you've flagged in a follow-up quiz. Most adjustments are small (a concentration shift, a new ingredient swapped in), but every batch is reviewed. The point isn't that the formula changes constantly — it's that the formula tracks you instead of you tracking it.

What if it doesn't work?

30-day money-back guarantee. No questions, no return shipping cost. If something isn't right, message your skincare advisor — most issues are solved by a formula adjustment, not a refund. Either way, the risk is on us.

Can I pause or cancel my subscription?

Anytime. Skip a shipment, change your cadence, pause for travel, or cancel — all in your account, no email or call required. The system reformulates whenever you reorder, even if there's a long gap between shipments.

How is this different from Curology?

Curology builds one prescription serum that treats one concern (typically acne or aging). PROVEN builds a full 3-step routine that treats every concern on your skin at once — main and secondary — and updates the formula based on your skin's progress and the season. Curology treats one thing. PROVEN treats all of it.

What if my skin is sensitive?

Sensitivity is one of the 47 factors the diagnostic reads. If your skin is reactive, your formula is built around lower-strength actives, barrier-rebuilding ingredients, and a sequence that introduces stronger components gradually. Customers with sensitive skin make up 41% of our subscriber base.

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